The Patriot Missile Failure
On February 25, 1991, during the Gulf War, an American Patriot Missile battery in Dharan, Saudi Arabia, failed to track and intercept an incoming Iraqi Scud missile. The Scud struck an American Army barracks, killing 28 soldiers and injuring around 100 other people. […] The small chopping error, when multiplied by the large number giving the time in tenths of a second, led to a significant error. Indeed, the Patriot battery had been up around 100 hours, and an easy calculation shows that the resulting time error due to the magnified chopping error was about 0.34 seconds. […] A Scud travels at about 1,676 meters per second, and so travels more than half a kilometer in this time. This was far enough that the incoming Scud was outside the “range gate” that the Patriot tracked.
Source: The Patriot Missile Failure